Source: NIH Office of Dietary Supplements — Vitamin B6 — RDA 1.3–1.7 mg; 25 mg supplemental is common (chronic high doses risk neuropathy; UL 100 mg).
High vs the RDA (1.3–1.7 mg); chronic B6 megadoses risk neuropathy.
The active, ready-to-use form of vitamin B6, a cofactor for over 100 enzymes.
Coenzyme for making serotonin, dopamine, GABA and more.
Important safety note: chronic high-dose B6 (typically >100–200 mg/day for months) can cause reversible nerve damage. Keep the dose modest — 25 mg is plenty.
| Per serving | |
|---|---|
| Typical branded single-ingredient product | $0.17 |
| Bulk powder at the clinical dose (100g, $21.97) | $0.01 |
Buying bulk powder instead of a branded bottle saves about 97% per serving.
Bulk price: $21.97/100g →Educational only — not medical advice. Grades and clinical doses are computed from public labels against sourced research (citations on the main site); prices last verified 2026-07-21. Expensive Powder has no sponsors; bulk links may earn an affiliate commission, which never affects a grade. Talk to a clinician before starting any supplement.