Ingredient guide · cognitive

Huperzine A

AChE inhibitor for memory & neuroprotection

The clinically studied dose

200mcg per day Studied

Source: Examine.com — Huperzine A — 50–200 mcg 1–2×/day; cycled due to its long-acting AChE inhibition.

What it is

A potent plant alkaloid that blocks the enzyme which breaks down acetylcholine.

What the research supports

How it works

Inhibits acetylcholinesterase, so acetylcholine lingers longer.

Side effects & safety

Potent and long-acting — cycle it (e.g., not daily). Can cause GI upset, cramps, vivid dreams. Don't combine with certain Alzheimer's drugs without medical advice.

What it should cost

Per serving
Typical branded single-ingredient product$0.50
Bulk powder at the clinical dose (10g 1%, $30.97)$0.06

Buying bulk powder instead of a branded bottle saves about 88% per serving.

Bulk price: $30.97/10g → Alt source: $12.99/5g

Graded products that contain it

Related ingredients

Educational only — not medical advice. Grades and clinical doses are computed from public labels against sourced research (citations on the main site); prices last verified 2026-07-21. Expensive Powder has no sponsors; bulk links may earn an affiliate commission, which never affects a grade. Talk to a clinician before starting any supplement.