Source: Examine.com — Betaine (TMG) — 2.5 g/day is the dose used in strength and power-output trials.
A methyl donor (trimethylglycine) derived from beets, used for performance and heart health.
Donates methyl groups for metabolism and acts as an osmolyte that hydrates cells.
Safe. High doses can cause GI upset or a fishy body odor. Well tolerated at the 2.5 g performance dose.
| Per serving | |
|---|---|
| Typical branded single-ingredient product | $0.42 |
| Bulk powder at the clinical dose (250g, $20.97) | $0.21 |
Buying bulk powder instead of a branded bottle saves about 50% per serving.
Bulk price: $20.97/250g →Educational only — not medical advice. Grades and clinical doses are computed from public labels against sourced research (citations on the main site); prices last verified 2026-07-21. Expensive Powder has no sponsors; bulk links may earn an affiliate commission, which never affects a grade. Talk to a clinician before starting any supplement.